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Atrial Heterogeneity Generates Re-entrant Substrate during Atrial Fibrillation and Anti-arrhythmic Drug Action: Mechanistic Insights from Canine Atrial Models

Anti-arrhythmic drug therapy is a frontline treatment for atrial fibrillation (AF), but its success rates are highly variable. This is due to incomplete understanding of the mechanisms of action of specific drugs on the atrial substrate at different stages of AF progression. We aimed to elucidate th...

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Detalles Bibliográficos
Autores principales: Varela, Marta, Colman, Michael A., Hancox, Jules C., Aslanidi, Oleg V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161306/
https://www.ncbi.nlm.nih.gov/pubmed/27984585
http://dx.doi.org/10.1371/journal.pcbi.1005245

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