Preclinical Efficacy and Safety Assessment of Artemisinin-Chemotherapeutic Agent Conjugates for Ovarian Cancer

Artemisinin (ARS) and its derivatives, which are clinically used antimalarial agents, have shown antitumor activities. Their therapeutic potencies, however, are limited by their low solubility and poor bioavailability. Here, through a pharmacophore hybridization strategy, we synthesized ARS-drug con...

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Detalles Bibliográficos
Autores principales: Li, Xiaoguang, Zhou, Yu, Liu, Yanling, Zhang, Xu, Chen, Tao, Chen, Kerong, Ba, Qian, Li, Jingquan, Liu, Hong, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161434/
https://www.ncbi.nlm.nih.gov/pubmed/27939426
http://dx.doi.org/10.1016/j.ebiom.2016.11.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161434/
https://www.ncbi.nlm.nih.gov/pubmed/27939426
http://dx.doi.org/10.1016/j.ebiom.2016.11.026

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