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Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection

HIV-1 infection occurs primarily through mucosal transmission. Application of biologically relevant mucosal models can advance understanding of the functional properties of antibodies that mediate HIV protection, thereby guiding antibody-based vaccine development. Here, we employed a human ex vivo v...

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Detalles Bibliográficos
Autores principales:	Astronomo, Rena D., Santra, Sampa, Ballweber-Fleming, Lamar, Westerberg, Katharine G., Mach, Linh, Hensley-McBain, Tiffany, Sutherland, Laura, Mildenberg, Benjamin, Morton, Georgeanna, Yates, Nicole L., Mize, Gregory J., Pollara, Justin, Hladik, Florian, Ochsenbauer, Christina, Denny, Thomas N., Warrier, Ranjit, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayapan, Sorachai, Kaewkungwal, Jaranit, Ferrari, Guido, Shaw, George M., Xia, Shi-Mao, Liao, Hua-Xin, Montefiori, David C., Tomaras, Georgia D., Haynes, Barton F., Juliana McElrath, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161443/ https://www.ncbi.nlm.nih.gov/pubmed/27919754 http://dx.doi.org/10.1016/j.ebiom.2016.11.024

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