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High Expression of CPT1A Predicts Adverse Outcomes: A Potential Therapeutic Target for Acute Myeloid Leukemia
Carnitine palmitoyl transferase 1A (CPT1A) protein catalyzes the rate-limiting step of Fatty-acid oxidation (FAO) pathway, which can promote cell proliferation and suppress apoptosis. Targeting CPT1A has shown remarkable anti-leukemia activity. But, its prognostic value remains unclear in Acute Myel...
Autores principales: | Shi, Jinlong, Fu, Huaping, Jia, Zhilong, He, Kunlun, Fu, Lin, Wang, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161445/ https://www.ncbi.nlm.nih.gov/pubmed/27916548 http://dx.doi.org/10.1016/j.ebiom.2016.11.025 |
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