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Transformation of temporal sequences in the zebra finch auditory system

This study examines how temporally patterned stimuli are transformed as they propagate from primary to secondary zones in the thalamorecipient auditory pallium in zebra finches. Using a new class of synthetic click stimuli, we find a robust mapping from temporal sequences in the primary zone to dist...

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Detalles Bibliográficos
Autores principales: Lim, Yoonseob, Lagoy, Ryan, Shinn-Cunningham, Barbara G, Gardner, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161447/
https://www.ncbi.nlm.nih.gov/pubmed/27897971
http://dx.doi.org/10.7554/eLife.18205
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author Lim, Yoonseob
Lagoy, Ryan
Shinn-Cunningham, Barbara G
Gardner, Timothy J
author_facet Lim, Yoonseob
Lagoy, Ryan
Shinn-Cunningham, Barbara G
Gardner, Timothy J
author_sort Lim, Yoonseob
collection PubMed
description This study examines how temporally patterned stimuli are transformed as they propagate from primary to secondary zones in the thalamorecipient auditory pallium in zebra finches. Using a new class of synthetic click stimuli, we find a robust mapping from temporal sequences in the primary zone to distinct population vectors in secondary auditory areas. We tested whether songbirds could discriminate synthetic click sequences in an operant setup and found that a robust behavioral discrimination is present for click sequences composed of intervals ranging from 11 ms to 40 ms, but breaks down for stimuli composed of longer inter-click intervals. This work suggests that the analog of the songbird auditory cortex transforms temporal patterns to sequence-selective population responses or ‘spatial codes', and that these distinct population responses contribute to behavioral discrimination of temporally complex sounds. DOI: http://dx.doi.org/10.7554/eLife.18205.001
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spelling pubmed-51614472016-12-19 Transformation of temporal sequences in the zebra finch auditory system Lim, Yoonseob Lagoy, Ryan Shinn-Cunningham, Barbara G Gardner, Timothy J eLife Neuroscience This study examines how temporally patterned stimuli are transformed as they propagate from primary to secondary zones in the thalamorecipient auditory pallium in zebra finches. Using a new class of synthetic click stimuli, we find a robust mapping from temporal sequences in the primary zone to distinct population vectors in secondary auditory areas. We tested whether songbirds could discriminate synthetic click sequences in an operant setup and found that a robust behavioral discrimination is present for click sequences composed of intervals ranging from 11 ms to 40 ms, but breaks down for stimuli composed of longer inter-click intervals. This work suggests that the analog of the songbird auditory cortex transforms temporal patterns to sequence-selective population responses or ‘spatial codes', and that these distinct population responses contribute to behavioral discrimination of temporally complex sounds. DOI: http://dx.doi.org/10.7554/eLife.18205.001 eLife Sciences Publications, Ltd 2016-11-29 /pmc/articles/PMC5161447/ /pubmed/27897971 http://dx.doi.org/10.7554/eLife.18205 Text en © 2016, Lim et al http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
Lim, Yoonseob
Lagoy, Ryan
Shinn-Cunningham, Barbara G
Gardner, Timothy J
Transformation of temporal sequences in the zebra finch auditory system
title Transformation of temporal sequences in the zebra finch auditory system
title_full Transformation of temporal sequences in the zebra finch auditory system
title_fullStr Transformation of temporal sequences in the zebra finch auditory system
title_full_unstemmed Transformation of temporal sequences in the zebra finch auditory system
title_short Transformation of temporal sequences in the zebra finch auditory system
title_sort transformation of temporal sequences in the zebra finch auditory system
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161447/
https://www.ncbi.nlm.nih.gov/pubmed/27897971
http://dx.doi.org/10.7554/eLife.18205
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