Increased intermediate M1-M2 macrophage polarization and improved cognition in mild cognitive impairment patients on ω-3 supplementation

Monocyte/macrophages of patients with mild cognitive impairment (MCI) and Alzheimer disease (AD) are defective in phagocytosis and degradation amyloid β(1–42) (Aβ(1–42)), but are improved by ω-3 fatty acids (ω-3s). The hypothesis of this study was that active Aβ(1–42) phagocytosis by macrophages pre...

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Detalles Bibliográficos
Autores principales: Famenini, Sam, Rigali, Elizabeth A., Olivera-Perez, Henry M., Dang, Johnny, Chang, Michael To, Halder, Ramesh, Rao, Rammohan V., Pellegrini, Matteo, Porter, Verna, Bredesen, Dale, Fiala, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161513/
https://www.ncbi.nlm.nih.gov/pubmed/27677546
http://dx.doi.org/10.1096/fj.201600677RR

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