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PAR1 Scaffolds TGFβRII to Downregulate TGF-β Signaling and Activate ESC Differentiation to Endothelial Cells

We studied the function of the G-protein-coupled receptor PAR1 in mediating the differentiation of mouse embryonic stem cells (mESCs) to endothelial cells (ECs) that are capable of inducing neovascularization. We observed that either deletion or activation of PAR1 suppressed mouse embryonic stem cel...

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Detalles Bibliográficos
Autores principales:	Gong, Haixia, An, Shejuan, Sassmann, Antonia, Liu, Menglin, Mastej, Victoria, Mittal, Manish, Zhang, Wei, Hong, Zhigang, Offermanns, Stefan, Rehman, Jalees, Malik, Asrar B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161529/ https://www.ncbi.nlm.nih.gov/pubmed/27866874 http://dx.doi.org/10.1016/j.stemcr.2016.10.006

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