Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas

Many solid cancers have an expanded CD44(+/hi)/CD24(−/low) cancer stem cell (CSC) population, which are relatively chemoresistant and drive recurrence and metastasis. Achieving a more durable response requires the development of therapies that specifically target CSCs. Recent evidence indicated that...

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Detalles Bibliográficos
Autores principales: Bogachek, Maria V., Park, Jung M., De Andrade, James P., Lorenzen, Allison W., Kulak, Mikhail V., White, Jeffrey R., Gu, Vivian W., Wu, Vincent T., Weigel, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161532/
https://www.ncbi.nlm.nih.gov/pubmed/27916539
http://dx.doi.org/10.1016/j.stemcr.2016.11.001

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