PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency

Primordial germ cells (PGCs) are specified from epiblast cells in mice. Genes associated with naive pluripotency are repressed in the transition from inner cell mass to epiblast cells, followed by upregulation after PGC specification. However, the molecular mechanisms underlying the reactivation of...

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Detalles Bibliográficos
Autores principales: Okashita, Naoki, Suwa, Yoshiaki, Nishimura, Osamu, Sakashita, Nao, Kadota, Mitsutaka, Nagamatsu, Go, Kawaguchi, Masanori, Kashida, Hiroki, Nakajima, Ayaka, Tachibana, Makoto, Seki, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161533/
https://www.ncbi.nlm.nih.gov/pubmed/27866876
http://dx.doi.org/10.1016/j.stemcr.2016.10.007

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