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p53 and p73 Regulate Apoptosis but Not Cell-Cycle Progression in Mouse Embryonic Stem Cells upon DNA Damage and Differentiation

Embryonic stem cells (ESCs) are fast proliferating cells capable of differentiating into all somatic cell types. In somatic cells, it is well documented that p53 is rapidly activated upon DNA damage to arrest the cell cycle and induce apoptosis. In mouse ESCs, p53 can also be functionally activated,...

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Detalles Bibliográficos
Autores principales:	He, Hanbing, Wang, Cheng, Dai, Qian, Li, Fengtian, Bergholz, Johann, Li, Zhonghan, Li, Qintong, Xiao, Zhi-Xiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161534/ https://www.ncbi.nlm.nih.gov/pubmed/27866875 http://dx.doi.org/10.1016/j.stemcr.2016.10.008

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