The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

Neutrophils, eosinophils and “classical” monocytes collectively account for ~70% of human blood leukocytes and are among the shortest-lived cells in the body(1,2). Precise regulation of the lifespan of these myeloid cells is critical to maintain protective immune responses while minimizing the delet...

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Detalles Bibliográficos
Autores principales: Kotzin, Jonathan J., Spencer, Sean P., McCright, Sam J., Kumar, Dinesh B. Uthaya, Collet, Magalie A., Mowel, Walter K., Elliott, Ellen N., Uyar, Asli, Makiya, Michelle A., Dunagin, Margaret C., Harman, Christian C.D., Virtue, Anthony T., Zhu, Stella, Bailis, Will, Stein, Judith, Hughes, Cynthia, Raj, Arjun, Wherry, E. John, Goff, Loyal A., Klion, Amy D., Rinn, John L., Williams, Adam, Flavell, Richard A., Henao-Mejia, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161578/
https://www.ncbi.nlm.nih.gov/pubmed/27525555
http://dx.doi.org/10.1038/nature19346

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