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Structural basis of kainate subtype glutamate receptor desensitization

Glutamate receptors are ligand gated tetrameric ion channels that mediate synaptic transmission in the central nervous system. They are instrumental in vertebrate cognition and their dysfunction underlies diverse diseases(1,2). In both the resting and desensitized states of AMPA and kainate subtype...

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Detalles Bibliográficos
Autores principales: Meyerson, Joel R., Chittori, Sagar, Merk, Alan, Rao, Prashant, Han, Tae Hee, Serpe, Mihaela, Mayer, Mark L., Subramaniam, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161608/
https://www.ncbi.nlm.nih.gov/pubmed/27580033
http://dx.doi.org/10.1038/nature19352

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