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Mosquito larvicide BinAB revealed by de novo phasing with an X-ray laser
BinAB is a naturally occurring paracrystalline larvicide distributed worldwide to combat the devastating diseases borne by mosquitoes. These crystals are composed of homologous molecules, BinA and BinB, which play distinct roles in the multi-step intoxication process, transforming from harmless, rob...
Autores principales: | Colletier, Jacques-Philippe, Sawaya, Michael R., Gingery, Mari, Rodriguez, Jose A., Cascio, Duilio, Brewster, Aaron S., Michels-Clark, Tara, Hice, Robert H., Coquelle, Nicolas, Boutet, Sébastien, Williams, Garth J., Messerschmidt, Marc, DePonte, Daniel P., Sierra, Raymond G., Laksmono, Hartawan, Koglin, Jason E., Hunter, Mark S., Park, Hyun-Woo, Uervirojnangkoorn, Monarin, Bideshi, Dennis K., Brunger, Axel T., Federici, Brian A., Sauter, Nicholas K., Eisenberg, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161637/ https://www.ncbi.nlm.nih.gov/pubmed/27680699 http://dx.doi.org/10.1038/nature19825 |
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