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Cell-Based Delivery of Interleukin-13 Directs Alternative Activation of Macrophages Resulting in Improved Functional Outcome after Spinal Cord Injury
The therapeutic effects of mesenchymal stem cell (MSC) transplantation following spinal cord injury (SCI) to date have been limited. Therefore, we aimed to enhance the immunomodulatory properties of MSCs via continuous secretion of the anti-inflammatory cytokine interleukin-13 (IL-13). By using MSCs...
Autores principales: | Dooley, Dearbhaile, Lemmens, Evi, Vangansewinkel, Tim, Le Blon, Debbie, Hoornaert, Chloé, Ponsaerts, Peter, Hendrix, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161742/ https://www.ncbi.nlm.nih.gov/pubmed/27974221 http://dx.doi.org/10.1016/j.stemcr.2016.11.005 |
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