USP10 Is an Essential Deubiquitinase for Hematopoiesis and Inhibits Apoptosis of Long-Term Hematopoietic Stem Cells

Self-renewal, replication, and differentiation of hematopoietic stem cells (HSCs) are regulated by cytokines produced by niche cells in fetal liver and bone marrow. HSCs must overcome stresses induced by cytokine deprivation during normal development. In this study, we found that ubiquitin-specific...

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Detalles Bibliográficos
Autores principales: Higuchi, Masaya, Kawamura, Hiroki, Matsuki, Hideaki, Hara, Toshifumi, Takahashi, Masahiko, Saito, Suguru, Saito, Kousuke, Jiang, Shuying, Naito, Makoto, Kiyonari, Hiroshi, Fujii, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161743/
https://www.ncbi.nlm.nih.gov/pubmed/27974222
http://dx.doi.org/10.1016/j.stemcr.2016.11.003

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