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A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming
Sexual reproduction culminates in a totipotent zygote with the potential to produce a whole organism. Sperm chromatin reorganization and epigenetic reprogramming that alter DNA and histone modifications generate a totipotent embryo. Active DNA demethylation of the paternal genome has been proposed t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cell Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161750/ https://www.ncbi.nlm.nih.gov/pubmed/27916276 http://dx.doi.org/10.1016/j.cell.2016.11.009 |