The retroviral RNA dimer linkage: different structures may reflect different roles

Retroviruses are unique among virus families in having dimeric genomes. The RNA sequences and structures that link the two RNA molecules vary, and these differences provide clues as to the role of this feature in the viral lifecycles. This review draws upon examples from different retroviral familie...

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Detalles Bibliográficos
Autor principal: Greatorex, Jane
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516450/
https://www.ncbi.nlm.nih.gov/pubmed/15317659
http://dx.doi.org/10.1186/1742-4690-1-22
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author Greatorex, Jane
author_facet Greatorex, Jane
author_sort Greatorex, Jane
collection PubMed
description Retroviruses are unique among virus families in having dimeric genomes. The RNA sequences and structures that link the two RNA molecules vary, and these differences provide clues as to the role of this feature in the viral lifecycles. This review draws upon examples from different retroviral families. Differences and similarities in both secondary and tertiary structure are discussed. The implication of varying roles for the dimer linkage in related viruses is considered.
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spelling pubmed-5164502004-09-10 The retroviral RNA dimer linkage: different structures may reflect different roles Greatorex, Jane Retrovirology Review Retroviruses are unique among virus families in having dimeric genomes. The RNA sequences and structures that link the two RNA molecules vary, and these differences provide clues as to the role of this feature in the viral lifecycles. This review draws upon examples from different retroviral families. Differences and similarities in both secondary and tertiary structure are discussed. The implication of varying roles for the dimer linkage in related viruses is considered. BioMed Central 2004-08-18 /pmc/articles/PMC516450/ /pubmed/15317659 http://dx.doi.org/10.1186/1742-4690-1-22 Text en Copyright © 2004 Greatorex; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Greatorex, Jane
The retroviral RNA dimer linkage: different structures may reflect different roles
title The retroviral RNA dimer linkage: different structures may reflect different roles
title_full The retroviral RNA dimer linkage: different structures may reflect different roles
title_fullStr The retroviral RNA dimer linkage: different structures may reflect different roles
title_full_unstemmed The retroviral RNA dimer linkage: different structures may reflect different roles
title_short The retroviral RNA dimer linkage: different structures may reflect different roles
title_sort retroviral rna dimer linkage: different structures may reflect different roles
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516450/
https://www.ncbi.nlm.nih.gov/pubmed/15317659
http://dx.doi.org/10.1186/1742-4690-1-22
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