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PD-L1 testing, fit for routine evaluation? From a pathologist’s point of view

Tumours with high somatic mutation rates escape immune surveillance by upregulating receptors and ligands such as programmed death receptor-1 and its ligand (PD-1/PD-L1). Checkpoint inhibitors (ICI) provide encouraging therapeutic results in non-small cell lung cancers (NSCLC) and may soon be used i...

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Detalles Bibliográficos
Autor principal: Hutarew, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165031/
https://www.ncbi.nlm.nih.gov/pubmed/28058063
http://dx.doi.org/10.1007/s12254-016-0292-2

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