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Expression Cloning and Production of Human Heavy-Chain-Only Antibodies from Murine Transgenic Plasma Cells

Several technologies have been developed to isolate human antibodies against different target antigens as a source of potential therapeutics, including hybridoma technology, phage and yeast display systems. For conventional antibodies, this involves either random pairing of VH and variable light (VL...

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Detalles Bibliográficos
Autores principales:	Drabek, Dubravka, Janssens, Rick, de Boer, Ernie, Rademaker, Rik, Kloess, Johannes, Skehel, John, Grosveld, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165034/ https://www.ncbi.nlm.nih.gov/pubmed/28066429 http://dx.doi.org/10.3389/fimmu.2016.00619

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