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The Cellular DNA Helicase ChlR1 Regulates Chromatin and Nuclear Matrix Attachment of the Human Papillomavirus 16 E2 Protein and High-Copy-Number Viral Genome Establishment
In papillomavirus infections, the viral genome is established as a double-stranded DNA episome. To segregate the episomes into daughter cells during mitosis, they are tethered to cellular chromatin by the viral E2 protein. We previously demonstrated that the E2 proteins of diverse papillomavirus typ...
Autores principales: | Harris, Leanne, McFarlane-Majeed, Laura, Campos-León, Karen, Roberts, Sally, Parish, Joanna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165203/ https://www.ncbi.nlm.nih.gov/pubmed/27795438 http://dx.doi.org/10.1128/JVI.01853-16 |
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