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Distinct Patterns of Tryptophan Maintenance in Tissues during Kynurenine Pathway Activation in Simian Immunodeficiency Virus-Infected Macaques

Induction of the kynurenine pathway (KP) of tryptophan (TRP) catabolism has been proposed to contribute to T cell dysfunction during human/simian immunodeficiency virus (SIV) infection via depletion of local TRP levels and production of immunomodulatory KP metabolites. However, while changes in TRP...

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Detalles Bibliográficos
Autores principales:	Drewes, Julia L., Croteau, Joshua D., Shirk, Erin N., Engle, Elizabeth L., Zink, M. C., Graham, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165277/ https://www.ncbi.nlm.nih.gov/pubmed/28066416 http://dx.doi.org/10.3389/fimmu.2016.00605

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