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Fast-SNP: a fast matrix pre-processing algorithm for efficient loopless flux optimization of metabolic models
Motivation: Computation of steady-state flux solutions in large metabolic models is routinely performed using flux balance analysis based on a simple LP (Linear Programming) formulation. A minimal requirement for thermodynamic feasibility of the flux solution is the absence of internal loops, which...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167067/ https://www.ncbi.nlm.nih.gov/pubmed/27559155 http://dx.doi.org/10.1093/bioinformatics/btw555 |