Niacin‐mediated Tace activation ameliorates CMT neuropathies with focal hypermyelination

Charcot–Marie–Tooth (CMT) neuropathies are highly heterogeneous disorders caused by mutations in more than 70 genes, with no available treatment. Thus, it is difficult to envisage a single suitable treatment for all pathogenetic mechanisms. Axonal Neuregulin 1 (Nrg1) type III drives Schwann cell mye...

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Detalles Bibliográficos
Autores principales: Bolino, Alessandra, Piguet, Françoise, Alberizzi, Valeria, Pellegatta, Marta, Rivellini, Cristina, Guerrero‐Valero, Marta, Noseda, Roberta, Brombin, Chiara, Nonis, Alessandro, D'Adamo, Patrizia, Taveggia, Carla, Previtali, Stefano Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167133/
https://www.ncbi.nlm.nih.gov/pubmed/27799291
http://dx.doi.org/10.15252/emmm.201606349

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