Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?

We present a case of a 36-year-old woman who developed a severe form of Idiopathic Pulmonary Arterial Hypertension (IPAH) during pregnancy and after emergency delivery. The management of IPAH during or after pregnancy is complex. Due to the severity of her IPAH, an upfront triple combination therapy...

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Detalles Bibliográficos
Autores principales: Paciocco, Giuseppe, Lombi, Andrea, Vincenzi, Antonella, Pesci, Alberto, Achilli, Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167241/
https://www.ncbi.nlm.nih.gov/pubmed/28018850
http://dx.doi.org/10.1016/j.rmcr.2016.11.011
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author Paciocco, Giuseppe
Lombi, Andrea
Vincenzi, Antonella
Pesci, Alberto
Achilli, Felice
author_facet Paciocco, Giuseppe
Lombi, Andrea
Vincenzi, Antonella
Pesci, Alberto
Achilli, Felice
author_sort Paciocco, Giuseppe
collection PubMed
description We present a case of a 36-year-old woman who developed a severe form of Idiopathic Pulmonary Arterial Hypertension (IPAH) during pregnancy and after emergency delivery. The management of IPAH during or after pregnancy is complex. Due to the severity of her IPAH, an upfront triple combination therapy, including i.v. epoprostenol, was started. The rapid institution of this treatment regimen allowed a complete right ventricular reverse remodelling after 1 year of therapy, leading to a down-titration until complete suspension of epoprostenol from the treatment regimen.
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spelling pubmed-51672412016-12-23 Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible? Paciocco, Giuseppe Lombi, Andrea Vincenzi, Antonella Pesci, Alberto Achilli, Felice Respir Med Case Rep Case Report We present a case of a 36-year-old woman who developed a severe form of Idiopathic Pulmonary Arterial Hypertension (IPAH) during pregnancy and after emergency delivery. The management of IPAH during or after pregnancy is complex. Due to the severity of her IPAH, an upfront triple combination therapy, including i.v. epoprostenol, was started. The rapid institution of this treatment regimen allowed a complete right ventricular reverse remodelling after 1 year of therapy, leading to a down-titration until complete suspension of epoprostenol from the treatment regimen. Elsevier 2016-11-24 /pmc/articles/PMC5167241/ /pubmed/28018850 http://dx.doi.org/10.1016/j.rmcr.2016.11.011 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Paciocco, Giuseppe
Lombi, Andrea
Vincenzi, Antonella
Pesci, Alberto
Achilli, Felice
Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?
title Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?
title_full Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?
title_fullStr Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?
title_full_unstemmed Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?
title_short Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?
title_sort right ventricular reverse remodelling in idiopathic pulmonary arterial hypertension diagnosed during pregnancy: is it possible?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167241/
https://www.ncbi.nlm.nih.gov/pubmed/28018850
http://dx.doi.org/10.1016/j.rmcr.2016.11.011
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