Cargando…

MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility

Epigenetic silencing by DNA methylation in brain tumors has been reported for many genes, however, their function on pathogenesis needs to be evaluated. We investigated the MTSS1 gene, identified as hypermethylated by differential methylation hybridization (DMH). Fifty-nine glioma tissue samples and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luxen, Daniel, Gielen, Gerrit H., Waha, Anke, Isselstein, Lukas, Müller, Tim, Koch, Philipp, Hammes, Jennifer, Becker, Albert, Simon, Matthias, Wurst, Peter, Endl, Elmar, Pietsch, Torsten, Gessi, Marco, Waha, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2016
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167248/ https://www.ncbi.nlm.nih.gov/pubmed/27988423 http://dx.doi.org/10.1016/j.tranon.2016.11.006

Ejemplares similares

Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas
por: Skubal, Magdalena, et al.
Publicado: (2016)

HGG-21. Oncogenic tyrosine kinase gene fusions in infant-type hemispheric gliomas - comparison of RNA- and DNA-based methods for their reliable detection
por: Pietsch, Torsten, et al.
Publicado: (2022)

Methylation class oligosarcoma may encompass IDH-wildtype gliomas
por: Ebrahimi, Azadeh, et al.
Publicado: (2022)

miRNA-182 regulated MTSS1 inhibits proliferation and invasion in Glioma Cells
por: Li, Zhexuan, et al.
Publicado: (2020)

HGG-34. DETECTION OF ONCOGENIC FUSION EVENTS IN SUPRATENTORIAL GLIOBLASTOMAS OF YOUNG CHILDREN
por: Pietsch, Torsten, et al.
Publicado: (2020)

Circular RNA SFMBT2 Inhibits the Proliferation and Metastasis of Glioma Cells Through Mir-182-5p/Mtss1 Pathway
por: Zhang, Shoudan, et al.
Publicado: (2020)

Long non-coding RNA MEG3 suppresses the growth of glioma cells by regulating the miR-96-5p/MTSS1 signaling pathway
por: Zhang, Shoudan, et al.
Publicado: (2019)

Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells
por: Glassmann, Alexander, et al.
Publicado: (2007)

Modulation of Motility and Proliferation of Glioma Cells by Hepatocyte Growth Factor
por: Yamamoto, Shinji, et al.
Publicado: (1997)

Epigenetic dysregulation in glioma
por: Kondo, Yutaka, et al.
Publicado: (2014)

H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components
por: Andreiuolo, Felipe, et al.
Publicado: (2019)

Analysis of TET Expression/Activity and 5mC Oxidation during Normal and Malignant Germ Cell Development
por: Nettersheim, Daniel, et al.
Publicado: (2013)

Post-radiation increase in VEGF enhances glioma cell motility in vitro
por: Kil, Whoon Jong, et al.
Publicado: (2012)

The role of brevican in glioma: promoting tumor cell motility in vitro and in vivo
por: Lu, Renquan, et al.
Publicado: (2012)

The Epigenetics of Glioma Stem Cells: A Brief Overview
por: Valor, Luis M., et al.
Publicado: (2020)

Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma
por: Hohm, Annika, et al.
Publicado: (2021)

MEOX2-mediated regulation of Cathepsin S promotes cell proliferation and motility in glioma
por: Wang, Ji, et al.
Publicado: (2022)

Mechanisms of invasion and motility of high-grade gliomas in the brain
por: Mair, Devin B., et al.
Publicado: (2018)

Downregulation of MTSS1 expression is an independent prognosticator in squamous cell carcinoma of the lung
por: Kayser, G, et al.
Publicado: (2015)

A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells
por: Barciszewska, Anna-Maria, et al.
Publicado: (2015)

Novel insights into the epigenetics of diffuse glioma
por: Danussi, Carla, et al.
Publicado: (2018)

CNS germinomas are characterized by global demethylation, chromosomal instability and mutational activation of the Kit-, Ras/Raf/Erk- and Akt-pathways
por: Schulte, Simone Laura, et al.
Publicado: (2016)

Autocrine Netrin Function Inhibits Glioma Cell Motility and Promotes Focal Adhesion Formation
por: Jarjour, Andrew A., et al.
Publicado: (2011)

Resveratrol Impairs Glioma Stem Cells Proliferation and Motility by Modulating the Wnt Signaling Pathway
por: Cilibrasi, Chiara, et al.
Publicado: (2017)

AJAP1 expression modulates glioma cell motility and correlates with tumor growth and survival
por: Di, Chunhui, et al.
Publicado: (2017)

Downregulated M6A modification and expression of circRNA_103239 promoted the progression of glioma by regulating the miR-182-5p/MTSS1 signalling pathway
por: Zhang, Shoudan, et al.
Publicado: (2023)

Epigenetic Modification and Differentiation Induction of Malignant Glioma Cells by Oligo-Fucoidan
por: Liao, Chien-Huang, et al.
Publicado: (2019)

Pediatric high-grade gliomas and the WHO CNS Tumor Classification—Perspectives of pediatric neuro-oncologists and neuropathologists in light of recent updates
por: Gielen, Gerrit H, et al.
Publicado: (2022)

Stimulation of glioma cell motility by expression, proteolysis, and release of the L1 neural cell recognition molecule
por: Yang, Muhua, et al.
Publicado: (2009)

Nuclear Motility in Glioma Cells Reveals a Cell-Line Dependent Role of Various Cytoskeletal Components
por: Kiss, Alexa, et al.
Publicado: (2014)

Potential Epigenetic-Based Therapeutic Targets for Glioma
por: Zang, Lanlan, et al.
Publicado: (2018)

Epigenetic age acceleration and clinical outcomes in gliomas
por: Zheng, Chunlei, et al.
Publicado: (2020)

Mtss1 Promotes Cell-Cell Junction Assembly and Stability through the Small GTPase Rac1
por: Dawson, John C., et al.
Publicado: (2012)

Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells
por: Dawson, John C., et al.
Publicado: (2011)

Glioma Stem Cells and Immunotherapy for the Treatment of Malignant Gliomas
por: Toda, Masahiro
Publicado: (2013)

Glioma Revisited: From Neurogenesis and Cancer Stem Cells to the Epigenetic Regulation of the Niche
por: de Almeida Sassi, Felipe, et al.
Publicado: (2012)

Non-coding RNAs as epigenetic regulator of glioma stem-like cell differentiation
por: Katsushima, Keisuke, et al.
Publicado: (2014)

Correction: Nuclear Motility in Glioma Cells Reveals a Cell-Line Dependent Role of Various Cytoskeletal Components
Publicado: (2014)

MTSS1 and SCAMP1 cooperate to prevent invasion in breast cancer
por: Vadakekolathu, Jayakumar, et al.
Publicado: (2018)

Loss of MTSS1 results in increased metastatic potential in pancreatic cancer
por: Zeleniak, Ann E, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ef5lnrqdik6c7l5qcuvbdhfpta