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Valosin‐containing Protein is a Target of 5′‐l Fuligocandin B and Enhances TRAIL Resistance in Cancer Cells

Fuligocandin B (2) is a novel natural product that can overcome TRAIL resistance. We synthesized enatiomerically pure fuligocandin B (2) and its derivative 5′‐I fuligocandin B (4), and found that the latter had an improved biological activity against the human gastric cancer cell line, AGS. We attac...

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Detalles Bibliográficos
Autores principales:	Arai, Midori A., Taguchi, Shota, Komatsuzaki, Kazuhiro, Uchiyama, Kento, Masuda, Ayaka, Sampei, Mana, Satoh, Mamoru, Kado, Sayaka, Ishibashi, Masami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167318/ https://www.ncbi.nlm.nih.gov/pubmed/28032027 http://dx.doi.org/10.1002/open.201600081

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