Cargando…

Prostaglandin D(2) Attenuates Bleomycin-Induced Lung Inflammation and Pulmonary Fibrosis

Pulmonary fibrosis is a progressive and fatal lung disease with limited therapeutic options. Although it is well known that lipid mediator prostaglandins are involved in the development of pulmonary fibrosis, the role of prostaglandin D(2) (PGD(2)) remains unknown. Here, we investigated whether gene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kida, Taiki, Ayabe, Shinya, Omori, Keisuke, Nakamura, Tatsuro, Maehara, Toko, Aritake, Kosuke, Urade, Yoshihiro, Murata, Takahisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167321/ https://www.ncbi.nlm.nih.gov/pubmed/27992456 http://dx.doi.org/10.1371/journal.pone.0167729

Ejemplares similares

Mast cell-derived prostaglandin D(2) limits the subcutaneous absorption of honey bee venom in mice
por: Fujiwara, Yuki, et al.
Publicado: (2023)

Prostaglandin D(2) metabolite in urine is an index of food allergy
por: Maeda, Shingo, et al.
Publicado: (2017)

Discovery of anti-inflammatory role of prostaglandin D(2): Veterinary Science Award Winner’s (No.118) Commemorative Review
por: MURATA, Takahisa, et al.
Publicado: (2016)

L-PGDS-produced PGD(2) in premature, but not in mature, adipocytes increases obesity and insulin resistance
por: Fujimori, Ko, et al.
Publicado: (2019)

The Leptomeninges Produce Prostaglandin D(2) Involved in Sleep Regulation in Mice
por: Cherasse, Yoan, et al.
Publicado: (2018)

Rapid degradation of cyclooxygenase-1 and hematopoietic prostaglandin D synthase through ubiquitin–proteasome system in response to intracellular calcium level
por: Yazaki, Misato, et al.
Publicado: (2012)

Biochemical, Functional, and Pharmacological Characterization of AT-56, an Orally Active and Selective Inhibitor of Lipocalin-type Prostaglandin D Synthase
por: Irikura, Daisuke, et al.
Publicado: (2009)

Tumor suppressor prostaglandin D(2)
por: Maeda, Shingo, et al.
Publicado: (2014)

Structural Basis of the Catalytic Mechanism Operating in Open-Closed Conformers of Lipocalin Type Prostaglandin D Synthase
por: Kumasaka, Takashi, et al.
Publicado: (2009)

Development of Monoclonal Antibody-Based EIA for Tetranor-PGDM which Reflects PGD(2) Production in the Body
por: Nagata, Nanae, et al.
Publicado: (2021)

Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D(2)
por: Nagata, Nanae, et al.
Publicado: (2017)

EP(2) and EP(4) receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals
por: Tajima, Tsuyoshi, et al.
Publicado: (2012)

Urinary 8-iso PGF(2α) and 2,3-dinor-8-iso PGF(2α) can be indexes of colitis-associated colorectal cancer in mice
por: Miyazaki, Yusuke, et al.
Publicado: (2021)

High-quality crystals of human haematopoietic prostaglandin D synthase with novel inhibitors
por: Takahashi, Sachiko, et al.
Publicado: (2010)

Improvement in the quality of hematopoietic prostaglandin D synthase crystals in a microgravity environment
por: Tanaka, Hiroaki, et al.
Publicado: (2011)

Inhibition of Prostaglandin F(2)(α) Receptors Exaggerates HCl-Induced Lung Inflammation in Mice
por: Maehara, Toko, et al.
Publicado: (2021)

High-Quality Protein Crystal Growth of Mouse Lipocalin-Type Prostaglandin D Synthase in Microgravity
por: Inaka, Koji, et al.
Publicado: (2011)

Efficient Attenuation of Dextran Sulfate Sodium-Induced Colitis by Oral Administration of 5,6-Dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic Acid in Mice
por: Takenouchi, Shinya, et al.
Publicado: (2021)

Attenuation of Laser-Induced Choroidal Neovascularization by Blockade of Prostaglandin D(2) Receptor 2
por: Soga, Hirotsugu, et al.
Publicado: (2023)

The profile of urinary lipid metabolites in healthy dogs
por: KIDA, Taiki, et al.
Publicado: (2022)

Octacosanol restores stress-affected sleep in mice by alleviating stress
por: Kaushik, Mahesh K., et al.
Publicado: (2017)

Microsomal Prostaglandin E Synthase-1 Deficiency Exacerbates Pulmonary Fibrosis Induced by Bleomycin in Mice
por: Wei, Bo, et al.
Publicado: (2014)

Roles of lipocalin-type and hematopoietic prostaglandin D synthases in mouse retinal angiogenesis
por: Horikami, Daiki, et al.
Publicado: (2023)

Vagotomy attenuates bleomycin-induced pulmonary fibrosis in mice
por: Song, Nana, et al.
Publicado: (2015)

Plumbagin attenuates Bleomycin-induced lung fibrosis in mice
por: Mehdizadeh, Saber, et al.
Publicado: (2022)

Imrecoxib attenuates bleomycin-induced pulmonary fibrosis in mice
por: Miao, Yang, et al.
Publicado: (2023)

Prostaglandin Transporter (PGT/SLCO2A1) Protects the Lung from Bleomycin-Induced Fibrosis
por: Nakanishi, Takeo, et al.
Publicado: (2015)

Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo
por: Huang, Tsung-Teng, et al.
Publicado: (2015)

Panax notoginseng Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Tsai, Kuen-Daw, et al.
Publicado: (2011)

Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice
por: Liu, Wei, et al.
Publicado: (2013)

Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis in rats
por: HE, HUANYU, et al.
Publicado: (2015)

Attenuation of Bleomycin-Induced Pulmonary Fibrosis in Rats with S-Allyl Cysteine
por: Tsukioka, Takuma, et al.
Publicado: (2017)

Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice
por: Huang, Jizhen, et al.
Publicado: (2020)

Thromboxane A(2) exacerbates acute lung injury via promoting edema formation
por: Kobayashi, Koji, et al.
Publicado: (2016)

Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D(2) Synthase as a Multifunctional Lipocalin
por: Urade, Yoshihiro
Publicado: (2021)

Urinary lipid profile of patients with coronavirus diseases 2019
por: Kida, Misato, et al.
Publicado: (2022)

Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin
por: Yamauchi, Keita, et al.
Publicado: (2011)

Comprehensive profiling of lipid metabolites in urine of canine patients with liver mass
por: KIDA, Taiki, et al.
Publicado: (2022)

Urinary lipid production profile in canine patients with splenic mass
por: KIDA, Taiki, et al.
Publicado: (2022)

Asarinin attenuates bleomycin-induced pulmonary fibrosis by activating PPARγ
por: Zeng, Qian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_g2oroe092g6o5i3r6rtfch80d7