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Rapid Naked‐Eye Discrimination of Cytochrome P450 Genetic Polymorphism through Non‐Crosslinking Aggregation of DNA‐Functionalized Gold Nanoparticles

The front cover artwork is provided by the group of Tohru Takarada at RIKEN (Japan). The image shows a colorimetric single‐nucleotide polymorphism (SNP) genotyping method that uses spontaneous aggregation of DNA‐modified gold nanoparticles (DNA–AuNPs) for the simple and rapid SNP genotyping of the h...

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Detalles Bibliográficos
Autores principales: Akiyama, Yoshitsugu, Wang, Guoqing, Shiraishi, Shota, Kanayama, Naoki, Takarada, Tohru, Maeda, Mizuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167336/
https://www.ncbi.nlm.nih.gov/pubmed/28032015
http://dx.doi.org/10.1002/open.201600142
Descripción
Sumario:The front cover artwork is provided by the group of Tohru Takarada at RIKEN (Japan). The image shows a colorimetric single‐nucleotide polymorphism (SNP) genotyping method that uses spontaneous aggregation of DNA‐modified gold nanoparticles (DNA–AuNPs) for the simple and rapid SNP genotyping of the human cytochrome P450 2C19 monooxygenase gene. For more details, read the full text of the Full Paper at p. 508.