Antinociceptive Effects of AGAP, a Recombinant Neurotoxic Polypeptide: Possible Involvement of the Tetrodotoxin-Resistant Sodium Channels in Small Dorsal Root Ganglia Neurons

Antitumor-analgesic peptide (AGAP) is a novel recombinant polypeptide. The primary study showed that AGAP 1.0 mg/kg exhibited strong analgesic and antitumor effects. The tail vein administration of AGAP potently reduced pain behaviors in mice induced by intraplantar injection of formalin or intraper...

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Detalles Bibliográficos
Autores principales: Li, Chun-Li, Liu, Xi-Fang, Li, Gui-Xia, Ban, Meng-qi, Chen, Jian-Zhao, Cui, Yong, Zhang, Jing-Hai, Wu, Chun-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168466/
https://www.ncbi.nlm.nih.gov/pubmed/28066245
http://dx.doi.org/10.3389/fphar.2016.00496

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