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Understanding Lung Deposition of Alpha-1 Antitrypsin in Acute Experimental Mouse Lung Injury Model Using Fluorescence Microscopy
Human plasma-derived α1-antitrypsin (AAT) delivered by intravenous infusion is used as augmentation therapy in patients with emphysema who have a genetic mutation resulting in deficiency of AAT. Inhalation is an alternative route of administration that can potentially increase the efficacy and conve...
Autores principales: | Wang, Mengmeng, Zhan, Yutian, Chen, Jianqing, Rong, Haojing, O'Neil, Shawn P., Ghosh, Brahma, Nguyen, Vuong, Owens, Jane, Li, Xianfeng, O'Hara, Denise M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168502/ https://www.ncbi.nlm.nih.gov/pubmed/28050284 http://dx.doi.org/10.1155/2016/5768312 |
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