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Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model
Bile acids, important mediators of lipid absorption, also act as hormone-like regulators and as antimicrobial molecules. In all these functions their potency is modulated by a variety of chemical modifications catalyzed by bacteria of the healthy gut microbiota, generating a complex variety of secon...
Autores principales: | Studer, Nicolas, Desharnais, Lyne, Beutler, Markus, Brugiroux, Sandrine, Terrazos, Miguel A., Menin, Laure, Schürch, Christian M., McCoy, Kathy D., Kuehne, Sarah A., Minton, Nigel P., Stecher, Bärbel, Bernier-Latmani, Rizlan, Hapfelmeier, Siegfried |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168579/ https://www.ncbi.nlm.nih.gov/pubmed/28066726 http://dx.doi.org/10.3389/fcimb.2016.00191 |
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