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Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study

OBJECTIVE: Studies evaluating caffeine intake during pregnancy and long-term outcomes, such as the child's neurobehaviour, are still scarce and their results are inconsistent. The objective of the present study was to evaluate the association between maternal consumption of caffeine during preg...

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Autores principales: Del-Ponte, Bianca, Santos, Iná S, Tovo-Rodrigues, Luciana, Anselmi, Luciana, Munhoz, Tiago N, Matijasevich, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168652/
https://www.ncbi.nlm.nih.gov/pubmed/27920084
http://dx.doi.org/10.1136/bmjopen-2016-012749
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author Del-Ponte, Bianca
Santos, Iná S
Tovo-Rodrigues, Luciana
Anselmi, Luciana
Munhoz, Tiago N
Matijasevich, Alicia
author_facet Del-Ponte, Bianca
Santos, Iná S
Tovo-Rodrigues, Luciana
Anselmi, Luciana
Munhoz, Tiago N
Matijasevich, Alicia
author_sort Del-Ponte, Bianca
collection PubMed
description OBJECTIVE: Studies evaluating caffeine intake during pregnancy and long-term outcomes, such as the child's neurobehaviour, are still scarce and their results are inconsistent. The objective of the present study was to evaluate the association between maternal consumption of caffeine during pregnancy and attention deficit hyperactivity disorder (ADHD) at the age of 11 years. METHODOLOGY: All children born in the city of Pelotas, Brazil, during the year 2004, were selected for a cohort study. The mothers were interviewed at birth to obtain information on coffee and yerba mate consumption during pregnancy, among other matters. At the age of 11 years, presence of ADHD was evaluated using the Development and Well-Being Assessment (DAWBA) questionnaire, applied to the mothers. The prevalence of ADHD was calculated, with 95% CIs. The association between caffeine consumption and ADHD was tested by means of logistic regression. RESULTS: 3485 children were included in the analyses. The prevalence of ADHD was 4.1% (95% CI 3.4% to 4.7%): 5.8% (95% CI 4.7% to 6.9%) among boys and 2.3% (95% CI 1.5% to 3.0%) among girls. The prevalence of caffeine consumption during the entire pregnancy and in the first, second and third trimesters was 88.7% (87.7% to 89.7%), 86.5% (85.4% to 87.5%), 83.0% (81.8% to 84.2%) and 92.3% (91.4% to 93.1%), respectively. Caffeine consumption during the entire pregnancy and the first, second and third trimesters were not associated with ADHD in the crude or adjusted analysis. CONCLUSIONS: The present study did not show any association between maternal caffeine consumption during pregnancy and ADHD at the age of 11 years.
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spelling pubmed-51686522016-12-22 Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study Del-Ponte, Bianca Santos, Iná S Tovo-Rodrigues, Luciana Anselmi, Luciana Munhoz, Tiago N Matijasevich, Alicia BMJ Open Epidemiology OBJECTIVE: Studies evaluating caffeine intake during pregnancy and long-term outcomes, such as the child's neurobehaviour, are still scarce and their results are inconsistent. The objective of the present study was to evaluate the association between maternal consumption of caffeine during pregnancy and attention deficit hyperactivity disorder (ADHD) at the age of 11 years. METHODOLOGY: All children born in the city of Pelotas, Brazil, during the year 2004, were selected for a cohort study. The mothers were interviewed at birth to obtain information on coffee and yerba mate consumption during pregnancy, among other matters. At the age of 11 years, presence of ADHD was evaluated using the Development and Well-Being Assessment (DAWBA) questionnaire, applied to the mothers. The prevalence of ADHD was calculated, with 95% CIs. The association between caffeine consumption and ADHD was tested by means of logistic regression. RESULTS: 3485 children were included in the analyses. The prevalence of ADHD was 4.1% (95% CI 3.4% to 4.7%): 5.8% (95% CI 4.7% to 6.9%) among boys and 2.3% (95% CI 1.5% to 3.0%) among girls. The prevalence of caffeine consumption during the entire pregnancy and in the first, second and third trimesters was 88.7% (87.7% to 89.7%), 86.5% (85.4% to 87.5%), 83.0% (81.8% to 84.2%) and 92.3% (91.4% to 93.1%), respectively. Caffeine consumption during the entire pregnancy and the first, second and third trimesters were not associated with ADHD in the crude or adjusted analysis. CONCLUSIONS: The present study did not show any association between maternal caffeine consumption during pregnancy and ADHD at the age of 11 years. BMJ Publishing Group 2016-12-05 /pmc/articles/PMC5168652/ /pubmed/27920084 http://dx.doi.org/10.1136/bmjopen-2016-012749 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Epidemiology
Del-Ponte, Bianca
Santos, Iná S
Tovo-Rodrigues, Luciana
Anselmi, Luciana
Munhoz, Tiago N
Matijasevich, Alicia
Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study
title Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study
title_full Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study
title_fullStr Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study
title_full_unstemmed Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study
title_short Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study
title_sort caffeine consumption during pregnancy and adhd at the age of 11 years: a birth cohort study
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168652/
https://www.ncbi.nlm.nih.gov/pubmed/27920084
http://dx.doi.org/10.1136/bmjopen-2016-012749
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