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Circulating cell-free DNA-based epigenetic assay can detect early breast cancer

BACKGROUND: Circulating cell-free DNA (cfDNA) has recently been recognized as a resource for biomarkers of cancer progression, treatment response, and drug resistance. However, few have demonstrated the usefulness of cfDNA for early detection of cancer. Although aberrant DNA methylation in cfDNA has...

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Detalles Bibliográficos
Autores principales: Uehiro, Natsue, Sato, Fumiaki, Pu, Fengling, Tanaka, Sunao, Kawashima, Masahiro, Kawaguchi, Kosuke, Sugimoto, Masahiro, Saji, Shigehira, Toi, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168705/
https://www.ncbi.nlm.nih.gov/pubmed/27993161
http://dx.doi.org/10.1186/s13058-016-0788-z