Performance of the G4 Xpert(®) MTB/RIF assay for the detection of Mycobacterium tuberculosis and rifampin resistance: a retrospective case-control study of analytical and clinical samples from high- and low-tuberculosis prevalence settings

BACKGROUND: The Xpert(®) MTB/RIF (Xpert) assay is a rapid PCR-based assay for the detection of Mycobacterium tuberculosis complex DNA (MTBc) and mutations associated with rifampin resistance (RIF). An updated version introduced in 2011, the G4 Xpert, included modifications to probe B and updated ana...

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Detalles Bibliográficos
Autores principales: Dharan, Nila J., Blakemore, Robert, Sloutsky, Alex, Kaur, Devinder, Alexander, Richard C., Ghajar, Minoo, Musser, Kimberlee A., Escuyer, Vincent E., Rowlinson, Marie-Claire, Crowe, Susanne, Laniado-Laborin, Rafael, Valli, Eloise, Nabeta, Pamela, Johnson, Pamela, Alland, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168809/
https://www.ncbi.nlm.nih.gov/pubmed/27993132
http://dx.doi.org/10.1186/s12879-016-2039-4

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