The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis

BACKGROUND: Altered tumor cell metabolism is an emerging hallmark of cancer; however, the precise role for glucose in tumor initiation is not known. GLUT1 (SLC2A1) is expressed in breast cancer cells and is likely responsible for avid glucose uptake observed in established tumors. We have shown that...

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Detalles Bibliográficos
Autores principales: Wellberg, Elizabeth A., Johnson, Stevi, Finlay-Schultz, Jessica, Lewis, Andrew S., Terrell, Kristina L., Sartorius, Carol A., Abel, E. Dale, Muller, William J., Anderson, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168867/
https://www.ncbi.nlm.nih.gov/pubmed/27998284
http://dx.doi.org/10.1186/s13058-016-0795-0

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