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Directed differentiation of human iPSC into insulin producing cells is improved by induced expression of PDX1 and NKX6.1 factors in IPC progenitors

BACKGROUND: Induced pluripotent stem cells (iPSC) possess an enormous potential as both, scientific and therapeutic tools. Their application in the regenerative medicine provides new treatment opportunities for numerous diseases, including type 1 diabetes. In this work we aimed to derive insulin pro...

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Detalles Bibliográficos
Autores principales:	Walczak, Maciej P., Drozd, Anna M., Stoczynska-Fidelus, Ewelina, Rieske, Piotr, Grzela, Dawid P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168869/ https://www.ncbi.nlm.nih.gov/pubmed/27998294 http://dx.doi.org/10.1186/s12967-016-1097-0

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