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Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526

The molecular mechanism underlying lifespan extension by resveratrol remains widely discussed. To help study this mechanism, we previously created resveratrol-enriched rice, DJ526, by transferring the resveratrol biosynthesis gene into Dongjin rice. DJ526 accumulates 1.4–1.9 μg g(−1) of resveratrol...

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Autores principales: Chung, Hea-Jong, Lee, Heui-Kwan, Kim, Hyeon-Jin, Baek, So-Hyeon, Hong, Seong-Tshool
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170592/
https://www.ncbi.nlm.nih.gov/pubmed/27996975
http://dx.doi.org/10.1038/sdata.2016.114
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author Chung, Hea-Jong
Lee, Heui-Kwan
Kim, Hyeon-Jin
Baek, So-Hyeon
Hong, Seong-Tshool
author_facet Chung, Hea-Jong
Lee, Heui-Kwan
Kim, Hyeon-Jin
Baek, So-Hyeon
Hong, Seong-Tshool
author_sort Chung, Hea-Jong
collection PubMed
description The molecular mechanism underlying lifespan extension by resveratrol remains widely discussed. To help study this mechanism, we previously created resveratrol-enriched rice, DJ526, by transferring the resveratrol biosynthesis gene into Dongjin rice. DJ526 accumulates 1.4–1.9 μg g(−1) of resveratrol in its grain and can ameliorates age-related deterioration in mice, as compared to control animals, based on assessments of motor coordination, physical strength and cutaneous tissue aging. Here, we present raw data sets, deposited in public repositories, from microarray analysis and physiological data of mice fed with DJ526 and Dongjin rice and treated with resveratrol. We also provide a method to analyze blood serum at micron levels. These data sets may help other researchers find new clues regarding the etiology of the anti-aging process and signaling pathways induced by resveratrol, rice, or DJ526.
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spelling pubmed-51705922016-12-27 Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526 Chung, Hea-Jong Lee, Heui-Kwan Kim, Hyeon-Jin Baek, So-Hyeon Hong, Seong-Tshool Sci Data Data Descriptor The molecular mechanism underlying lifespan extension by resveratrol remains widely discussed. To help study this mechanism, we previously created resveratrol-enriched rice, DJ526, by transferring the resveratrol biosynthesis gene into Dongjin rice. DJ526 accumulates 1.4–1.9 μg g(−1) of resveratrol in its grain and can ameliorates age-related deterioration in mice, as compared to control animals, based on assessments of motor coordination, physical strength and cutaneous tissue aging. Here, we present raw data sets, deposited in public repositories, from microarray analysis and physiological data of mice fed with DJ526 and Dongjin rice and treated with resveratrol. We also provide a method to analyze blood serum at micron levels. These data sets may help other researchers find new clues regarding the etiology of the anti-aging process and signaling pathways induced by resveratrol, rice, or DJ526. Nature Publishing Group 2016-12-20 /pmc/articles/PMC5170592/ /pubmed/27996975 http://dx.doi.org/10.1038/sdata.2016.114 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0 Metadata associated with this Data Descriptor is available at http://www.nature.com/sdata/ and is released under the CC0 waiver to maximize reuse.
spellingShingle Data Descriptor
Chung, Hea-Jong
Lee, Heui-Kwan
Kim, Hyeon-Jin
Baek, So-Hyeon
Hong, Seong-Tshool
Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526
title Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526
title_full Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526
title_fullStr Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526
title_full_unstemmed Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526
title_short Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526
title_sort gene expression profiles and physiological data from mice fed resveratrol-enriched rice dj526
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170592/
https://www.ncbi.nlm.nih.gov/pubmed/27996975
http://dx.doi.org/10.1038/sdata.2016.114
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