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RNA sequencing analysis of the developing chicken retina

RNA sequencing transcriptome analysis using massively parallel next generation sequencing technology provides the capability to understand global changes in gene expression throughout a range of tissue samples. Development of the vertebrate retina requires complex temporal orchestration of transcrip...

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Autores principales: Langouet-Astrie, Christophe J., Meinsen, Annamarie L., Grunwald, Emily R., Turner, Stephen D., Enke, Raymond A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170595/
https://www.ncbi.nlm.nih.gov/pubmed/27996968
http://dx.doi.org/10.1038/sdata.2016.117
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author Langouet-Astrie, Christophe J.
Meinsen, Annamarie L.
Grunwald, Emily R.
Turner, Stephen D.
Enke, Raymond A.
author_facet Langouet-Astrie, Christophe J.
Meinsen, Annamarie L.
Grunwald, Emily R.
Turner, Stephen D.
Enke, Raymond A.
author_sort Langouet-Astrie, Christophe J.
collection PubMed
description RNA sequencing transcriptome analysis using massively parallel next generation sequencing technology provides the capability to understand global changes in gene expression throughout a range of tissue samples. Development of the vertebrate retina requires complex temporal orchestration of transcriptional activation and repression. The chicken embryo (Gallus gallus) is a classic model system for studying developmental biology and retinogenesis. Existing retinal transcriptome projects have been critical to the vision research community for studying aspects of murine and human retinogenesis, however, there are currently no publicly available data sets describing the developing chicken retinal transcriptome. Here we used Illumina RNA sequencing (RNA-seq) analysis to characterize the mRNA transcriptome of the developing chicken retina in an effort to identify genes critical for retinal development in this important model organism. These data will be valuable to the vision research community for characterizing global changes in gene expression between ocular tissues and critical developmental time points during retinogenesis in the chicken retina.
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spelling pubmed-51705952016-12-27 RNA sequencing analysis of the developing chicken retina Langouet-Astrie, Christophe J. Meinsen, Annamarie L. Grunwald, Emily R. Turner, Stephen D. Enke, Raymond A. Sci Data Data Descriptor RNA sequencing transcriptome analysis using massively parallel next generation sequencing technology provides the capability to understand global changes in gene expression throughout a range of tissue samples. Development of the vertebrate retina requires complex temporal orchestration of transcriptional activation and repression. The chicken embryo (Gallus gallus) is a classic model system for studying developmental biology and retinogenesis. Existing retinal transcriptome projects have been critical to the vision research community for studying aspects of murine and human retinogenesis, however, there are currently no publicly available data sets describing the developing chicken retinal transcriptome. Here we used Illumina RNA sequencing (RNA-seq) analysis to characterize the mRNA transcriptome of the developing chicken retina in an effort to identify genes critical for retinal development in this important model organism. These data will be valuable to the vision research community for characterizing global changes in gene expression between ocular tissues and critical developmental time points during retinogenesis in the chicken retina. Nature Publishing Group 2016-12-20 /pmc/articles/PMC5170595/ /pubmed/27996968 http://dx.doi.org/10.1038/sdata.2016.117 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0 Metadata associated with this Data Descriptor is available at http://www.nature.com/sdata/ and is released under the CC0 waiver to maximize reuse.
spellingShingle Data Descriptor
Langouet-Astrie, Christophe J.
Meinsen, Annamarie L.
Grunwald, Emily R.
Turner, Stephen D.
Enke, Raymond A.
RNA sequencing analysis of the developing chicken retina
title RNA sequencing analysis of the developing chicken retina
title_full RNA sequencing analysis of the developing chicken retina
title_fullStr RNA sequencing analysis of the developing chicken retina
title_full_unstemmed RNA sequencing analysis of the developing chicken retina
title_short RNA sequencing analysis of the developing chicken retina
title_sort rna sequencing analysis of the developing chicken retina
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170595/
https://www.ncbi.nlm.nih.gov/pubmed/27996968
http://dx.doi.org/10.1038/sdata.2016.117
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