The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage

Chromatin relaxation is one of the earliest cellular responses to DNA damage. However, what determines these structural changes, including their ATP requirement, is not well understood. Using live-cell imaging and laser microirradiation to induce DNA lesions, we show that the local chromatin relaxat...

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Detalles Bibliográficos
Autores principales: Sellou, Hafida, Lebeaupin, Théo, Chapuis, Catherine, Smith, Rebecca, Hegele, Anna, Singh, Hari R., Kozlowski, Marek, Bultmann, Sebastian, Ladurner, Andreas G., Timinszky, Gyula, Huet, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170603/
https://www.ncbi.nlm.nih.gov/pubmed/27733626
http://dx.doi.org/10.1091/mbc.E16-05-0269

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