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GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge
The mechanism of directional cell migration remains an important problem, with relevance to cancer invasion and metastasis. GOLPH3 is a common oncogenic driver of human cancers, and is the first oncogene that functions at the Golgi in trafficking to the plasma membrane. Overexpression of GOLPH3 is r...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170606/ https://www.ncbi.nlm.nih.gov/pubmed/27708138 http://dx.doi.org/10.1091/mbc.E16-01-0005 |