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The cAMP pathway regulates mRNA decay through phosphorylation of the RNA-binding protein TIS11b/BRF1

TPA-inducible sequence 11b/butyrate response factor 1 (TIS11b/BRF1) belongs to the tristetraprolin (TTP) family of zinc-finger proteins, which bind to mRNAs containing AU-rich elements in their 3′-untranslated region and target them for degradation. Regulation of TTP family function through phosphor...

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Detalles Bibliográficos
Autores principales: Rataj, Felicitas, Planel, Séverine, Desroches-Castan, Agnès, Le Douce, Juliette, Lamribet, Khadija, Denis, Josiane, Feige, Jean-Jacques, Cherradi, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170607/
https://www.ncbi.nlm.nih.gov/pubmed/27708140
http://dx.doi.org/10.1091/mbc.E16-06-0379