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Moesin and cortactin control actin-dependent multivesicular endosome biogenesis

We used in vivo and in vitro strategies to study the mechanisms of multivesicular endosome biogenesis. We found that, whereas annexinA2 and ARP2/3 mediate F-actin nucleation and branching, respectively, the ERM protein moesin supports the formation of F-actin networks on early endosomes. We also fou...

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Detalles Bibliográficos
Autores principales:	Muriel, Olivia, Tomas, Alejandra, Scott, Cameron C., Gruenberg, Jean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170863/ https://www.ncbi.nlm.nih.gov/pubmed/27605702 http://dx.doi.org/10.1091/mbc.E15-12-0853

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