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Divergent Synthesis and Real-Time Biological Annotation of Optically Active Tetrahydrocyclopenta[c]pyranone Derivatives
[Image: see text] Sp(3)-rich compounds are underrepresented in libraries for probe- and drug-discovery, despite their promise of extending the range of accessible molecular shapes beyond planar geometries. With this in mind, a collection of single-enantiomer bicyclic, fused cyclopentenones underpinn...
Autores principales: | Nelson, Shawn D., Wawer, Mathias J., Schreiber, Stuart L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171204/ https://www.ncbi.nlm.nih.gov/pubmed/27978655 http://dx.doi.org/10.1021/acs.orglett.6b03118 |
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