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Persistent p55TNFR expression impairs T cell responses during chronic tuberculosis and promotes reactivation

The pleiotropic activities of TNF are mediated by two structurally related but functionally distinct type I transmembrane receptors, p55TNFR and p75TNFR expressed in most cell types, that can be cleaved and act as TNF scavengers. Here, we investigated the effect of persistent p55TNFR cell surface ex...

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Detalles Bibliográficos
Autores principales:	Dambuza, Ivy M., Keeton, Roanne, Hsu, Nai-Jen, Allie, Nasiema, Quesniaux, Valérie F. J., Ryffel, Bernhard, Jacobs, Muazzam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171238/ https://www.ncbi.nlm.nih.gov/pubmed/27995986 http://dx.doi.org/10.1038/srep39499

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