Translational regulation of APOBEC3G mRNA by Vif requires its 5′UTR and contributes to restoring HIV-1 infectivity

The essential HIV-1 viral infectivity factor (Vif) allows productive infection of non-permissive cells expressing cytidine deaminases APOBEC3G (A3G) and A3F by decreasing their cellular level, and preventing their incorporation into virions. Unlike the Vif-induced degradation of A3G, the functional...

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Detalles Bibliográficos
Autores principales: Guerrero, Santiago, Libre, Camille, Batisse, Julien, Mercenne, Gaëlle, Richer, Delphine, Laumond, Géraldine, Decoville, Thomas, Moog, Christiane, Marquet, Roland, Paillart, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171582/
https://www.ncbi.nlm.nih.gov/pubmed/27996044
http://dx.doi.org/10.1038/srep39507

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