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PRKAR1A is a functional tumor suppressor inhibiting ERK/Snail/E-cadherin pathway in lung adenocarcinoma

Protein Kinase cAMP-Dependent Regulatory Type I Alpha (PRKAR1A) is a tissue-specific extinguisher that transduces a signal through phosphorylation of different target proteins. Loss of PRKAR1A was frequently observed in endocrine neoplasia and stromal cell tumors. However, a few cases were seen in e...

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Detalles Bibliográficos
Autores principales: Wang, Shaoqiang, Cheng, Yuanda, Zheng, Yingying, He, Zhiwei, Chen, Wei, Zhou, Wolong, Duan, Chaojun, Zhang, Chunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171641/
https://www.ncbi.nlm.nih.gov/pubmed/27995993
http://dx.doi.org/10.1038/srep39630

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