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Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation

Dendritic cells (DCs) have been implicated in the pathogenesis of psoriasis but the roles for specific DC subsets are not well defined. Here we show that DCs are required for psoriasis-like changes in mouse skin induced by the local injection of IL-23. However, Flt3L-dependent DCs and resident Lange...

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Detalles Bibliográficos
Autores principales:	Singh, Tej Pratap, Zhang, Howard H., Borek, Izabela, Wolf, Peter, Hedrick, Michael N., Singh, Satya P., Kelsall, Brian L., Clausen, Bjorn E., Farber, Joshua M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171657/ https://www.ncbi.nlm.nih.gov/pubmed/27982014 http://dx.doi.org/10.1038/ncomms13581

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