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ALK: a tyrosine kinase target for cancer therapy

The anaplastic lymphoma kinase (ALK) gene plays an important physiologic role in the development of the brain and can be oncogenically altered in several malignancies, including non-small-cell lung cancer (NSCLC) and anaplastic large cell lymphomas (ALCL). Most prevalent ALK alterations are chromoso...

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Detalles Bibliográficos
Autores principales: Holla, Vijaykumar R., Elamin, Yasir Y., Bailey, Ann Marie, Johnson, Amber M., Litzenburger, Beate C., Khotskaya, Yekaterina B., Sanchez, Nora S., Zeng, Jia, Shufean, Md Abu, Shaw, Kenna R., Mendelsohn, John, Mills, Gordon B., Meric-Bernstam, Funda, Simon, George R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171696/
https://www.ncbi.nlm.nih.gov/pubmed/28050598
http://dx.doi.org/10.1101/mcs.a001115