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PI16 is a shear stress and inflammation-regulated inhibitor of MMP2
Raised endothelial shear stress is protective against atherosclerosis but such protection may be lost at sites of inflammation. We found that four splice variants of the peptidase inhibitor 16 (PI16) mRNA are among the most highly shear stress regulated transcripts in human coronary artery endotheli...
Autores principales: | Hazell, Georgina G. J., Peachey, Alasdair M. G., Teasdale, Jack E., Sala-Newby, Graciela B., Angelini, Gianni D., Newby, Andrew C., White, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171773/ https://www.ncbi.nlm.nih.gov/pubmed/27996045 http://dx.doi.org/10.1038/srep39553 |
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