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PI16 is a shear stress and inflammation-regulated inhibitor of MMP2

Raised endothelial shear stress is protective against atherosclerosis but such protection may be lost at sites of inflammation. We found that four splice variants of the peptidase inhibitor 16 (PI16) mRNA are among the most highly shear stress regulated transcripts in human coronary artery endotheli...

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Detalles Bibliográficos
Autores principales: Hazell, Georgina G. J., Peachey, Alasdair M. G., Teasdale, Jack E., Sala-Newby, Graciela B., Angelini, Gianni D., Newby, Andrew C., White, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171773/
https://www.ncbi.nlm.nih.gov/pubmed/27996045
http://dx.doi.org/10.1038/srep39553

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