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Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis

Hemorrhagic cystitis is an inflammatory and ulcerative bladder condition associated with systemic chemotherapeutics, like cyclophosphomide. Earlier, we reported reactive oxygen species resulting from cyclophosphamide metabolite, acrolein, causes global methylation followed by silencing of DNA damage...

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Detalles Bibliográficos
Autores principales: Haldar, Subhash, Dru, Christopher, Mishra, Rajeev, Tripathi, Manisha, Duong, Frank, Angara, Bryan, Fernandez, Ana, Arditi, Moshe, Bhowmick, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171776/
https://www.ncbi.nlm.nih.gov/pubmed/27995963
http://dx.doi.org/10.1038/srep39257